Original articles AMEC 2001-2004

Surgery

Head of Department:
Prof. Dr. med. Robert Grützmann, MBA

Naschberger E, Werner T, Vicente AB, Guenzi E, Töpolt K, Leubert R, Lubeseder-Martellato C, Nelson PJ, Stürzl M. Nuclear factor-kappaB motif and interferon-alpha-stimulated response element co-operate in the activation of guanylate-binding protein-1 expression by inflammatory cytokines in endothelial cells. Biochem J. 2004 Apr 15;379(Pt 2):409-20.

Matzen K, Dirkx AE, oude Egbrink MG, Speth C, Götte M, Ascherl G, Grimm T, Griffioen AW, Stürzl M.HIV-1 Tat increases the adhesion of monocytes and T-cells to the endothelium in vitro and in vivo: implications for AIDS-associated vasculopathy. Virus Res. 2004 Sep 1;104(2):145-55.

Guenzi E, Töpolt K, Lubeseder-Martellato C, Jörg A, Naschberger E, Benelli R, Albini A, Stürzl M. The guanylate binding protein-1 GTPase controls the invasive and angiogenic capability of endothelial cells through inhibition of MMP-1 expression. EMBO J. 2003 Aug 1;22(15):3772-82.

Lubeseder-Martellato C, Guenzi E, Jörg A, Töpolt K, Naschberger E, Kremmer E, Zietz C, Tschachler E, Hutzler P, Schwemmle M, Matzen K, Grimm T, Ensoli B, Stürzl M.Guanylate-binding protein-1 expression is selectively induced by inflammatory cytokines and is an activation marker of endothelial cells during inflammatory diseases. Am J Pathol. 2002 Nov;161(5):1749-59.

Zietz C, Rumpler U, Stürzl M, Löhrs U.Inverse relation of Fas-ligand and tumor-infiltrating lymphocytes in angiosarcoma: indications of apoptotic tumor counterattack. Am J Pathol. 2001 Sep;159(3):963-70.

Toschi E, Barillari G, Sgadari C, Bacigalupo I, Cereseto A, Carlei D, Palladino C, Zietz C, Leone P, Stürzl M, Buttò S, Cafaro A, Monini P, Ensoli B.Activation of matrix-metalloproteinase-2 and membrane-type-1-matrix-metalloproteinase in endothelial cells and induction of vascular permeability in vivo by human immunodeficiency virus-1 Tat protein and basic fibroblast growth factor. Mol Biol Cell. 2001 Oct;12(10):2934-46.

Stürzl M, Zietz C, Monini P, Ensoli B.Human herpesvirus-8 and Kaposi's sarcoma: relationship with the multistep concept of tumorigenesis. Adv Cancer Res. 2001;81:125-59. Review.

Schatz O, Monini P, Bugarini R, Neipel F, Schulz TF, Andreoni M, Erb P, Eggers M, Haas J, Buttò S, Lukwiya M, Bogner JR, Yaguboglu S, Sheldon J, Sarmati L, Goebel FD, Hintermaier R, Enders G, Regamey N, Wernli M, Stürzl M, Rezza G, Ensoli B.Kaposi's sarcoma-associated herpesvirus serology in Europe and Uganda: multicentre study with multiple and novel assays. J Med Virol. 2001 Sep;65(1):123-32.

Rimessi P, Bonaccorsi A, Stürzl M, Fabris M, Brocca-Cofano E, Caputo A, Melucci-Vigo G, Falchi M, Cafaro A, Cassai E, Ensoli B, Monini P.Transcription pattern of human herpesvirus 8 open reading frame K3 in primary effusion lymphoma and Kaposi's sarcoma. J Virol. 2001 Aug;75(15):7161-74.

Monini P, Sirianni MC, Franco M, Vincenzi L, Topino S, Goletti D, Leone P, Leone P, Chiozzini C, Nicastri E, Andreoni M, Borduagni O, Sgadari C, Rezza G, Stürzl M, Ensoli B.Clearance of human herpesvirus 8 from blood and regression of leukopenia-associated aggressive classic Kaposi's sarcoma during interferon-alpha therapy: a case report. Clin Infect Dis. 2001 Nov 15;33(10):1782-5.

Guenzi E, Töpolt K, Cornali E, Lubeseder-Martellato C, Jörg A, Matzen K, Zietz C, Kremmer E, Nappi F, Schwemmle M, Hohenadl C, Barillari G, Tschachler E, Monini P, Ensoli B, Stürzl M.The helical domain of GBP-1 mediates the inhibition of endothelial cell proliferation by inflammatory cytokines. EMBO J. 2001 Oct 15;20(20):5568-77.

Ensoli B, Sgadari C, Barillari G, Sirianni MC, Stürzl M, Monini P.Biology of Kaposi's sarcoma. Eur J Cancer. 2001 Jul;37(10):1251-69. Review.

Ensoli B, Stürzl M, Monini P.Reactivation and role of HHV-8 in Kaposi's sarcoma initiation. Adv Cancer Res. 2001;81:161-200. Review.

Ascherl G, Sgadari C, Bugarini R, Bogner J, Schatz O, Ensoli B, Stürzl M.Serum concentrations of fibroblast growth factor 2 are increased in HIV type 1-infected patients and inversely related to survival probability. AIDS Res Hum Retroviruses. 2001 Jul 20;17(11):1035-9.

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